WebTerm: FHF complex. Definition: A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex). … WebThe FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. The mouse homolog of this gene produces …
AP4M1 - AP-4 complex subunit mu-1 - Function - neXtProt
WebFeb 2, 2004 · The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) (PubMed:18799622). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997). Required for spermatid differentiation. WebIPR019384 FHF complex subunit HOOK interacting protein. IPR045669 FHF complex subunit HOOK interacting protein, C-terminal. IPR045668 FHF complex subunit HOOK interacting protein, KELAA motif. Molecular Reagents less. All nucleic 14. cDNA 14. Microarray probesets 4. Other Accession IDs less. MGI:1923495 References more. le tape malaysia 2023
An FTS/Hook/p107FHIP Complex Interacts with and Promotes
http://amigo.geneontology.org/amigo/term/GO:0070695 WebNov 12, 2024 · In particular, FAM160A2 (also known as FHIP), is a component of the FTS/Hook/FHIP complex (FHF complex), which functions to promote vesicle trafficking and/or fusion via the homotypic-vesicular ... WebMay 5, 2001 · FHF/IB2 interaction and FHF-dependent IB2/p38δ interaction suggested the formation of a FHF/IB2/p38δ trimeric complex. Evidence for such trimeric complexes was obtained using lysates from cells cotransfected with FHF-2, p38δ, and either wild-type IB2 or a mutant derivative lacking the major FHF-binding domain, IB2 Δ212–471 . le tanneron mimosiste